1,2,4-Thiadiazol-5-amine, 3-(4-pyridinyl)-
3-(4-Pyridinyl)-1,2,4-thiadiazol-5-amine
CAS: 35115-35-6
Molecular Formula: C7H6N4S
1,2,4-Thiadiazol-5-amine, 3-(4-pyridinyl)- - Names and Identifiers
| Name | 3-(4-Pyridinyl)-1,2,4-thiadiazol-5-amine |
| Synonyms | 3-(4-Pyridinyl)-1,2,4-thiadiazol-5-amine 3-(4-Pyridinyl)-5-aMino-[1,2,4]thiadiazole 1,2,4-Thiadiazol-5-amine, 3-(4-pyridinyl)- |
| CAS | 35115-35-6 |
1,2,4-Thiadiazol-5-amine, 3-(4-pyridinyl)- - Physico-chemical Properties
| Molecular Formula | C7H6N4S |
| Molar Mass | 178.21 |
| Storage Condition | Room Temprature |
| Sensitive | Irritant |
| MDL | MFCD09865004 |
1,2,4-Thiadiazol-5-amine, 3-(4-pyridinyl)- - Introduction
3-(4-Pyridinyl)-1,2,4-thiadiazol-5-amine is an organic compound with the chemical formula C8H7N5S. The following is its nature, use, preparation and safety information:
Nature:
-Appearance: 3-(4-Pyridinyl)-1,2,4-thiadiazol-5-amine is a solid substance, commonly known as white crystalline powder.
-Solubility: It has good solubility in common organic solvents (such as chloroform, ethanol, etc.).
-Stability: It is relatively stable under normal storage conditions.
Use:
- 3-(4-Pyridinyl)-1,2,4-thiadiazol-5-amine is commonly used as an intermediate in organic synthesis. It has potential anti-tumor and antibacterial activities in the field of medicine, and can be used to develop new drugs.
-It can also be used as a synthetic precursor for dyes and pigments because it can provide nitrogen and sulfur hybrid ring structures.
Preparation Method:
The synthesis of 3-(4-Pyridinyl)-1,2,4-thiadiazol-5-amine can be carried out by the following steps:
1. First, the nitrosotoluene (p-nitrotoluene) and sulfamide (sulfamide) are reacted to obtain 5-nitro-1,2,4-thiadiazole (5-nitro-1,2,4-thiadiazole).
2. Next, 5-nitro-1, 2,4-thiadiazole is reacted with benzenemagnesium iodide (phenylmagnesium) to form 5-benzyl-1,2,4-thiadiazole (5-benzyl-1,2,4-thiadiazole).
3. Finally, 5-benzyl -1,2,4-thiadiazole was reacted with 4-pyridinecarboxaldehyde (4-pyridinyl aldehyde) to obtain the final product 3-(4-Pyridinyl)-1,2,4-thiadiazol-5-amine.
Safety Information:
- 3-(4-Pyridinyl)-1,2,4-thiadiazol-5-amine is required to comply with routine laboratory safety practices during use and storage.
-It should be stored in a dry, well-ventilated place, and avoid contact with oxidants, strong acids, strong bases and other substances.
-When operating, be sure to wear appropriate personal protective equipment, such as laboratory gloves, eye protection glasses, etc.
Please note that to ensure safety and accuracy, the correct operating instructions and safety data sheets (SDS) should be followed when using and handling chemicals.
Nature:
-Appearance: 3-(4-Pyridinyl)-1,2,4-thiadiazol-5-amine is a solid substance, commonly known as white crystalline powder.
-Solubility: It has good solubility in common organic solvents (such as chloroform, ethanol, etc.).
-Stability: It is relatively stable under normal storage conditions.
Use:
- 3-(4-Pyridinyl)-1,2,4-thiadiazol-5-amine is commonly used as an intermediate in organic synthesis. It has potential anti-tumor and antibacterial activities in the field of medicine, and can be used to develop new drugs.
-It can also be used as a synthetic precursor for dyes and pigments because it can provide nitrogen and sulfur hybrid ring structures.
Preparation Method:
The synthesis of 3-(4-Pyridinyl)-1,2,4-thiadiazol-5-amine can be carried out by the following steps:
1. First, the nitrosotoluene (p-nitrotoluene) and sulfamide (sulfamide) are reacted to obtain 5-nitro-1,2,4-thiadiazole (5-nitro-1,2,4-thiadiazole).
2. Next, 5-nitro-1, 2,4-thiadiazole is reacted with benzenemagnesium iodide (phenylmagnesium) to form 5-benzyl-1,2,4-thiadiazole (5-benzyl-1,2,4-thiadiazole).
3. Finally, 5-benzyl -1,2,4-thiadiazole was reacted with 4-pyridinecarboxaldehyde (4-pyridinyl aldehyde) to obtain the final product 3-(4-Pyridinyl)-1,2,4-thiadiazol-5-amine.
Safety Information:
- 3-(4-Pyridinyl)-1,2,4-thiadiazol-5-amine is required to comply with routine laboratory safety practices during use and storage.
-It should be stored in a dry, well-ventilated place, and avoid contact with oxidants, strong acids, strong bases and other substances.
-When operating, be sure to wear appropriate personal protective equipment, such as laboratory gloves, eye protection glasses, etc.
Please note that to ensure safety and accuracy, the correct operating instructions and safety data sheets (SDS) should be followed when using and handling chemicals.
Last Update：2024-04-09 21:01:54
